The Science of Gut Health & Digestion

Nutribliss Digestive Enzyme Blend with Makzyme-Pro™

This formula provides a broad spectrum of digestive enzymes designed to help the body break down macronutrients like protein, fat, and carbohydrates for better nutrient absorption and digestive comfort. Shop Digestive Enzyme Blend →

Ingredient: Makzyme-Pro™ & Enzyme Blend

Makzyme-Pro™ is a technology that includes a buffer to help protect the enzymes and probiotics from stomach acid, supporting their delivery to the small intestine where they are most effective.

Evidence for Support of Macronutrient Digestion

• Supplemental Enzymes for Digestion.
  REVIEW ARTICLE
  Citation: Ianiro, G., Pecere, S., Giorgio, V., Gasbarrini, A., & Cammarota, G. (2016). Digestive Enzyme Supplementation in Gastrointestinal Diseases. Current drug metabolism, 17(2), 187–193.
  [PUBMED]

  This review discusses the clinical application of supplemental enzymes, including:
  • Proteases (like Bromelain, Papain) for protein digestion.
  • Lipases for fat digestion.
  • Amylases and Alpha-Galactosidase for carbohydrate digestion.
  • Lactase for lactose (milk sugar) digestion.

Nutribliss Probiotics with MAKTREK®

This high-potency synbiotic formula combines four clinically researched probiotic strains with prebiotics to support a healthy gut microbiome, immune function, and digestive balance. Shop Probiotics →

This formula utilizes MAKTREK® Bi-Pass Technology, a natural marine polysaccharide complex that protects the live probiotic organisms from stomach acid. It also includes Fructooligosaccharides (FOS), a prebiotic fiber that serves as fuel for beneficial gut bacteria.

Ingredient: Lactobacillus acidophilus (La-14)

Evidence for Support of Gut Health and Immunity

• Effect of a probiotic on the vaginal microbiota.
  HUMAN CLINICAL TRIAL
  Citation: De Alberti, D., Russo, R., Terruzzi, F., Nobile, V., & Ouwehand, A. C. (2015). Effect of a multi-strain probiotic formulation on the vaginal microbiota of healthy women. Beneficial microbes, 6(4), 483-487.
  [PUBMED]

Ingredient: Bifidobacterium lactis (Bl-04)

Evidence for Support of Healthy Immune Response

• Probiotic effects on cold and influenza-like symptom incidence and duration in healthy adults.
  HUMAN CLINICAL TRIAL
  Citation: West, N. P., Horn, P. L., Pyne, D. B., Gebski, V. J., Lahtinen, S. J., Fricker, P. A., & Cripps, A. W. (2014). Probiotic supplementation for respiratory and gastrointestinal illness symptoms in healthy physically active individuals. Clinical nutrition (Edinburgh, Scotland), 33(4), 581–587.
  [PUBMED]

Ingredient: Lactobacillus plantarum (Lp-115)

Evidence for Support of Gut Barrier Function

• Probiotic administration affects the gut-brain axis and improves anxiety.
  HUMAN CLINICAL TRIAL
  Citation: Lew, L. C., Hor, Y. Y., Yusoff, N. A., Choi, S. B., Yusoff, M. S. B., Roslan, N. S., ... & Liong, M. T. (2019). Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety in adults: a randomised, double-blind, placebo-controlled study. Beneficial microbes, 10(4), 355-373.
  [PUBMED]

  Note: While this study uses a different L. plantarum strain (P8), it demonstrates the known mechanisms of this species in supporting gut-brain axis communication. Lp-115 is specifically included in formulations for its adhesion properties and ability to support a healthy microbial balance.

Ingredient: Lactobacillus paracasei (Lpc-37)

Evidence for Support of Psychological and Physiological Stress Markers

• Probiotic Lactobacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults.
  HUMAN CLINICAL TRIAL
  Citation: Patterson, E., O'Riordan, K. J., Iannone, F., et al. (2020). Probiotic Lactobacillus paracasei Lpc-37® improves psychological and physiological markers of stress and anxiety in healthy adults: a randomized, double-blind, placebo-controlled and parallel clinical trial. Neurobiology of stress, 13, 100277.
  [PUBMED]